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Topic: CV and mad panic behaviour (Read 438987 times) previous topic - next topic
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Re: CV and mad panic behaviour

Reply #6285 –
Help might be on the way!

Melbourne researchers trial use of common blood-thinning drug heparin to combat COVID-19, abc.net.au.

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Nearly two years later, with the help of researchers at Melbourne, Monash and Oxford Universities, his team has been able to replicate international findings that heparin can block the transmission of COVID-19 and prevent infection.

The spray coats the nose but does not go down into the lungs. The researchers say it is cheap, easy to distribute and is expected to be effective against mutant strains of the virus including the Omicron variant.

"It won't matter if a new variant comes along, this drug will block that protein from infecting the cells," Professor Campbell said.

"I'm very confident that we can demonstrate that it will work, and people will be using this before they go to the shops and before they go to school."
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Director of the Medicines Manufacturing Innovation Centre at Monash University, Michelle McIntosh, has spent the past 20 months working on the best possible formulation for the nasal spray.

She said some coronavirus vaccines had limited distribution in some countries because they needed to be stored at ultra-low temperatures.

"One of the wonderful things about heparin is it is already available on the market as an approved product for another purpose, it doesn't require refrigeration and can be stored in plastic vials so it can be distributed very widely and effectively," Professor McIntosh said.

"We are not proposing this as an alternative to a vaccination, it is a supplement for people who can't be vaccinated, but we do imagine it will be very widely used."

Re: CV and mad panic behaviour

Reply #6286 –
Irrespective of where you sit on covid, our hospitals run as lean as possible at the best of times.  They know how many are coming, what demographics, why they are likely to come and have planned to within a degree of additional capacity if and when required.

Covid has the ability to cause bedlam to that.  Think of what happened supply chain wise last year.  Everything is geared to a just in time and just enough for manufacturing.  Likewise health care to make it as resource efficient as possible.

 Anyone ever seen a hospital waiting room empty?  13 years ive been in 2 different health services and the one take away i have for everyone is whilst the model is scalable its not easy to do so for a variety of factors.

Add a pandemic with even a moderate kick up in care and presentations and you result in a lot of issues.
"everything you know is wrong"

Paul Hewson

Re: CV and mad panic behaviour

Reply #6287 –
Speak to people in various industries and retail - supply chains were/are at close to collapse eg the Adblue debacle.   Seen the empty seatainer farms at Altona etc?  Just handling and moving stuff ATM is difficult.
DrE is no more... you ok with that harmonica man?

Re: CV and mad panic behaviour

Reply #6288 –
Quote from: Mav on
The Public Health Unit of the University of NSW predicted 25,000 new cases a day in NSW by the end of January (while noting the prediction doesn't factor in booster shots). Bracing though these predictions might be, they highlight what exponential growth means. Another way of seeing the same phenomenon is by looking at the huge spike in actual daily figures from the UK.
All the models have to be judged in a frame of reference for the model, for example some are "if all restrictions are removed", while others base themselves on "restrictions as currently applied" and adopted.

The media just lump all the reporting and modelling in as "like for like" but it isn't, it's not the epidemiologists that are confused or in error, it's the media and also how the media is manipulated for political purposes. But it's pretty easy to cut through all that spin if you choose to do so!

The media will take a worst case scenario and report it as the peak and infer a high probability, when it reality it's the peak with a very low probability. All the predictions fall on a bell curve of some sort, even when you see a hyperbolic or parabolic curve it's usually just a subsection of a larger bell curve.
The Force Awakens!

Re: CV and mad panic behaviour

Reply #6289 –
Yep, in this case the modelling assumes no attempts at suppressing spread. That means it's a worst-case scenario. Ordinarily you'd think that means it's ridiculous as governments will be forced to act. But who knows what will happen in NSW? Perrotet seems committed to ditching any restrictions. And such predictions are a useful counter to those who say we should just let it rip and learn to live with the virus. They're in a bizarre situation of saying "Don't worry about those dire predictions as the Govt won't let it rip" and then later saying that the interventions were unnecessary and useless and we should have just let it rip.

Re: CV and mad panic behaviour

Reply #6290 –
Nobody's questioning Parrotsay's rhetoric, but it appears to be laying the foundations for deflecting blame for decisions made on economic basis over welfare.

Also, not much is being written about the low reported NSW death rate versus Vic, lower numbers in Vic for week and weeks now with proportionally higher deaths. The naysayers will claim Dan has inflated he figures, but I suspect it's more likely Parrotsay has done the exact opposite. The reason for me forming this opinion is that there seems to be a disconnect between the duress reported by NSW Health / Hospital staff and Parrotsay's reported death rates. Something seems a bit stinky!

Statistically, it should approach the national / global average once you have enough cases on a regular basis, but NSW seems to be delivering a Christmas miracle, have they have beaten the math or are they calling a spade a surfboard? Note that as of yesterday in NSW Omicron was still not yet the dominant strain but as a percentage it's rising very fast.
The Force Awakens!

Re: CV and mad panic behaviour

Reply #6291 –
3,763 new cases in NSW, 1,503 new cases in Vic. Will this be like the recent Delta outbreak where we ended up overtaking NSW?

Re: CV and mad panic behaviour

Reply #6292 –
Quote from: Mav on
3,763 new cases in NSW, 1,503 new cases in Vic. Will this be like the recent Delta outbreak where we ended up overtaking NSW?
Geographically, probably that is going to be the case, but I'm not sure if Omicron follows the same rules regarding polar proximity.
The Force Awakens!

Re: CV and mad panic behaviour

Reply #6293 –
I'll wait and see what winter brings in the northern hemisphere.  They're lousy numbers already and so many countries have been lying about their figures.  180,000 cases in the States yesterday, 1800 deaths.  And climbing. 

Re: CV and mad panic behaviour

Reply #6294 –
Around 2 weeks ago (7/12/22), there were 297 cases in hospital (47 in ICU) in Victoria.

Today, there are 394 cases in hospital (70 in ICU), an increase of around 32% and 49% respectively.

Re: CV and mad panic behaviour

Reply #6295 –
Interesting to read the Heparin claims being made in the media, I wonder what the dose is for treating Sars-CoV-2, but it's hard to see it used prophylactically given the potential bad effects of over-use.

So I presume they are talking a boutique treatment for those people with COVID who qualify as candidates.

Given strokes / haemorrhages are a potential side-effect of heparin, is it wise to be spraying up your nose in the close proximity to or bypassing the blood / brain barrier?

FYI
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One way to bypass the blood brain barrier and thus treat diseases of the brain is to use the nasal route of administration and deposit drugs at the olfactory region of the nares, from where they travel to the brain via mechanisms that are still not clearly understood, with travel across nerve fibers and travel via a perivascular pathway both being hypothesized.
The Force Awakens!

Re: CV and mad panic behaviour

Reply #6296 –
Different rules for elite tennis players and public plebs it seems...Comrade Dan and Craig Tilley have organised medical exemptions for certain players unnamed to be allowed to play the Aus open, The Djoker being one of the prime suspects and they dont even have to state their vaccination status unless they choose to do so...
Seems the privacy of elite tennis players is more important than the health of Victorians..but hang on we do have Dan's anti Magna Carta Pandemic Legislation to save us......

No medical exemption for Russian tennis player Natalia Vikhlyantseva though ,forced to miss the grand slam because her vaccine isn't recognised by Australian authorities.
Vikhlyantseva, who was set to compete in qualifying for the Melbourne Park tournament in January, is vaccinated with the Sputnik V vaccine.
They must think with that rocket fuel vaccine in her body she might be a fire hazard.....
 

Re: CV and mad panic behaviour

Reply #6297 –
Would he be missed?  

Re: CV and mad panic behaviour

Reply #6298 –
Quote from: capcom on
Would he be missed?  
The money is what they might miss,  the SA Govt are allowing a tennis tournament for the ladies to go ahead as well, with players quarantined in Victoria at the minute. If they are vaccinated then fine but Vic city folk are still locked out of SA I believe and when you have different rules for different folk where exemptions are based on the money doing the talking then you leave yourself open for criticism. People have been prevented from seeing critically ill loved ones etc yet sporting events that make big money or carry prestige are allowed to continue and that applies to all state governments.
With Omicron in its early days here in Aus you would think some consistency in rules would apply across the board and if players wont get vaccinated then they forfeit the right to play..

Re: CV and mad panic behaviour

Reply #6299 –
Saved again ... by a rampant idiot just now on channel 9.  She pleaded with the boxing day crowd not to shout on if you happen to be masked at the MCG should you infect someone else.  Where did they dig up these nitwits?  Back to your knitting dear