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Re: CV and mad panic behaviour

Reply #5355 –
Quote from: spf – on
Dr. John Campbell discusses Covid immunity - Natural versus vaccine immunity.
Dr Campbell's conclusions make an even stronger case for cross vaccination, and they support the idea that B and T cell development is even stronger in people who have had any two exposures to either, Sars-CoV-2, AZ or Pfizer.

This isn't new information, there have been many virologists and epidemiologists pushing this stance for many months now, but it's being largely ignored by the media and as such it gathers zero political momentum.

Interestingly, the new GSK and Merck wonder drugs for treating Sars-CoV-2, might inhibit or diminish B and T cell production, the studies looking into that are really just beginning. I don't know if those concerns are founded in any substantial science or not, just that it is being looked at, the suggestion does have a feel to it not unlike the vaccine disinformation that Merck and GSK happily allowed to circulate early on, a bit of doubt about competitor products never hurts the bottom line!
"Ruck, ruck, ruck, ruck ....... Ruck, ruck, ruck, ruck"

Re: CV and mad panic behaviour

Reply #5356 –
Quote from: Thryleon – on
My sister has 3 kids in primary school and luckily for her I was able to repurpose some items marked for disposal and give her access two laptops she could use for them else they were dividing up 2 computers among 5 people to use for home schooling and working from home.
As an aside to this last point, I've been helping guys at work setup Raspberry Pi 4b for use at home for their kids and grandchildren. You can get a kit including a case and cables for under about $150, and you end up with a NUC style Debian Linux box that runs LibreOffice, etc., on any HDMI capable display.  The biggest expense is often keyboard and mouse if you have to add them in assuming you can't get hold of old ones, the Logitech K400s work quite well as a combo and can be found quite cheaply. Because Raspian is targeted at young kids learning to be coders, even though oldies can use it for IoT dev, it's setup to be quite simple to manage compared to a normal Debian distro, and has some useful generic controls for printers, WiFi, etc., etc.. You still need to have a home WiFi or Ethernet setup, because at that price there is no real-time clock in those devices, so they get the date and time off the network. Being Linux, and being Raspberry PI, they are also easy to pre-configure in kiosk mode so that a power cycle cleans all the garbage.

In a decade or so we might have a whole generation of tech heads come out of this pandemic!
"Ruck, ruck, ruck, ruck ....... Ruck, ruck, ruck, ruck"

Re: CV and mad panic behaviour

Reply #5357 –
Epidemiologist warns Covid will spread ‘like wildfire’ in Victoria if rules are relaxed now,news.com.au

Quote
An epidemiologist has poured cold water on calls by business groups and others to overhaul Victoria’s isolation rules, saying any change would cause the virus to spread “like wildfire”.

Nancy Baxter also says the reason the state’s outbreak is being controlled is because of the stay-at-home requirement, despite the focus on vaccination.

...

“The lower we can keep the numbers, the safer we can keep our hospitals, so when we do open up, we have the space to put the patients that are going to increase, because because of openings.”

Dr Baxter said before the AFL grand final long weekend she hoped Victoria would beat predictions by getting vaccinated as quickly as possible and bring numbers down.

But a failure by Victorians to abide by rules helped drive the outbreak.

“All of us know people who are not following the rules and most of the time they get away with it,” she said.

“But the more people in our community that have COVID, the more the chances that they’re not going to get away with it and they’re going to fuel the outbreak.

“I do think the narrative is a bit precious that somehow the government is to blame for the increase in people in isolation, when actually it’s because we’re not following the rules and the cases are spreading, and so there’s more people in isolation.”
 

Re: CV and mad panic behaviour

Reply #5361 –
Quote from: PaulP – on
What are your opinions on Yanis Varoufakis ?

I actually thought quite highly of him from the few times I heard him speak, but the reality is as follows.  As an Australian born to Greek migrants, I recognise that Greeces national politics are driven by geopolitical factors, which leaves governing Greece stuck between a rock and a hard place, where you are constantly having to bend to the whims of others as an otherwise small economic and military player in a region that is dominated by your neighbours.  I am also more likely to be shaped by the opinions of my family members who have their own opinions driven by their own anecdotal experiences with life.  I use their political spectrum as an example, because now that you mention Varoufakis, I forgot all about the middle left Syriza, who have been dominated by policies and ideologies more alligned with far left ideology.  The best and brightest minds have been fleeing Greece for generations, and their workforce hampered by rampant nepotism.  They have a long way to go as a nation, but the challenges are enormous.  Makes me wonder whether or not the monarchy in exile was in the nations best interests because since then they have had a military Junta, and then decades of left leaning politicians, which has resulted in a rather dramatic shift back towards nationalism almost a necessity. 

Anyway, Im glad he resigned when he did, as it showed him as being one of the few constituants of politics who seems to have left Greek politics with their reputation relatively in tact, BUT even that fact depends on whom you ask!


Quote from: LP – on
As an aside to this last point, I've been helping guys at work setup Raspberry Pi 4b for use at home for their kids and grandchildren. You can get a kit including a case and cables for under about $150, and you end up with a NUC style Debian Linux box that runs LibreOffice, etc., on any HDMI capable display.  The biggest expense is often keyboard and mouse if you have to add them in assuming you can't get hold of old ones, the Logitech K400s work quite well as a combo and can be found quite cheaply. Because Raspian is targeted at young kids learning to be coders, even though oldies can use it for IoT dev, it's setup to be quite simple to manage compared to a normal Debian distro, and has some useful generic controls for printers, WiFi, etc., etc.. You still need to have a home WiFi or Ethernet setup, because at that price there is no real-time clock in those devices, so they get the date and time off the network. Being Linux, and being Raspberry PI, they are also easy to pre-configure in kiosk mode so that a power cycle cleans all the garbage.

In a decade or so we might have a whole generation of tech heads come out of this pandemic!

Future generations are by default more involved with technology which would have occurred with or without the pandemic (evidenced by our last 30 years), and the global chip shortage isnt solely about computers.  money is only half the problem when an organisation like ours is waiting greater than 6 months for new devices because HP cant supply to keep up with demand. 
"everything you know is wrong"

Paul Hewson

Re: CV and mad panic behaviour

Reply #5362 –
Thanks Thry.

Re: CV and mad panic behaviour

Reply #5363 –
EU could start review of Covid pill ‘in days’ - FROM THE H/S (this is the 'anti-viral drugs being spoken about recently)

The EU’s medicines watchdog could within days start a review of an oral Covid drug produced by the US pharmaceutical firm Merck, a senior official said on Tuesday local time.

Merck said last week that its drug molnupiravir was shown to reduce hospitalisations by 50 per cent, bringing closer the dream of a simple pill to treat the coronavirus pandemic.

“What I can say is that indeed we will be considering whether to start a rolling review for this compound in the next days,” Marco Cavaleri, head of vaccine strategy at the European Medicines Agency, told journalists.

Cavaleri said the Amsterdam-based agency was aware of some “top-line results that are being communicated by the company” about its new drug.

Merck said on Friday it planned to submit an application to the US FDA and other regulatory bodies worldwide for the drug.

It said trial results on 770 patients showed there were no deaths among patients who received the drug compared to eight deaths in the placebo group.

Under a rolling review, the EMA can speed up drug approvals by examining safety and efficacy data as they are released, instead of waiting until after a formal application for authorisation is filed by the manufacturer.

Approval can take several months.

The Merck pill has been hailed as a possible breakthrough because until now Covid therapeutics — which treat the disease as opposed to vaccines, which prevent it — have so far been administered intravenously.

The EMA meanwhile raised hopes that vaccine booster doses could offer a long period of protection against Covid.

The agency on Monday authorised a third booster dose of the Pfizer/BioNTech vaccine for people aged 18 and over, six months after their initial two jabs, amid fears that it offers diminishing protection.

“What we’re seeing at least with this vaccine is that the immune response is indeed much higher than what we’ve seen after the second dose,” Cavaleri said.

“Which means that potentially we will have quite remarkable amounts of neutralising antibodies, also for much longer than six months.”

Re: CV and mad panic behaviour

Reply #5364 –
Dr. John Campbell discusses 'Antiviral game changer' - Merck and Ridgeback.

  • Oral Antiviral, molnupiravir (MK-4482, EIDD-2801)
  • Positive Interim Analysis of Phase 3 Study
  • Significantly reduced the risk of hospitalization or death
  • During day 1 to 5 to 29 days
  • Phase 3 MOVe-OUT trial

https://youtu.be/qVW2QqHUJUw

Re: CV and mad panic behaviour

Reply #5365 –
How come we aren't seeing a flurry of social media posts about Sweden and Denmark halting the use of Moderna for u18s.

Given how quickly social media and news media piled on AZ it seems a tad selective in reporting?

I've been posting here that the side-effects although different for Pfizer/Moderna are as comparable common as those for AZ, it's been known for almost 6 months since the initial trial results surfaced.

Why are Sweden and Denmark taking this stance now?

Is it just coincidence that it happens just as GSK and Merck issue remedies, am I justified in being cynical?

Someone always profits from a little bit of corporate doubt.
"Ruck, ruck, ruck, ruck ....... Ruck, ruck, ruck, ruck"

Re: CV and mad panic behaviour

Reply #5366 –
Quote from: LP – on
How come we aren't seeing a flurry of social media posts about Sweden and Denmark halting the use of Moderna for u18s.

Given how quickly social media and news media piled on AZ it seems a tad selective in reporting?

I've been posting here that the side-effects although different for Pfizer/Moderna are as comparable common as those for AZ, it's been known for almost 6 months since the initial trial results surfaced.

Why are Sweden and Denmark taking this stance now?

Is it just coincidence that it happens just as GSK and Merck issue remedies, am I justified in being cynical?

Someone always profits from a little bit of corporate doubt.

It was the second story on the heraldsun website.
2012 HAPPENED!!!!!!!

Re: CV and mad panic behaviour

Reply #5367 –
I'm guessing it would have been number 1 if the HS wasn't contractually bound to run a Dictator Dan article in the top slot  :))

Re: CV and mad panic behaviour

Reply #5368 –
Quote from: madbluboy – on
It was the second story on the heraldsun website.
The coverage is trivial compared the AZ blood clots saga.

I remain convinced some of this rumour comes from within the industry, it's the same tactic we saw used against AZ, J&J , Novavax and Sputnik. The Moderna side-effects were exposed in the clinical trials and they are virtually identical to Pfizer, which in number are virtually identical to AZ, J&J, Novavax and Sputnik.

That little bit of doubt means that countries change what they buy, this is what it is all about, it has nothing to do with real world effects or emergencies.

Notice recently things have gone quiet locally about AZ, because as the vaccinations levels increase it turns out for some reason as yet unknown locally issued AZ is even safer than OS results! There is some thought it comes down to genetics and also domestic trends in other related medications, like the type of pain killers we use here compared to other countries.
"Ruck, ruck, ruck, ruck ....... Ruck, ruck, ruck, ruck"

Re: CV and mad panic behaviour

Reply #5369 –
^^  follow moderna's share price and that will give you a better answer.

Contrast with Pfizer.

Pre pandemic vs post pandemic.

Then you realise that AZ is being produced by CSL and the CSL share price hasnt really taken much of a hit during covid.

;)
"everything you know is wrong"

Paul Hewson