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Topic: CV and mad panic behaviour (Read 886089 times) previous topic - next topic
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Re: CV and mad panic behaviour

Reply #6000 –
I’m not sure I’d be placing much faith in the indo govs accounting.
Let’s go BIG !

Re: CV and mad panic behaviour

Reply #6001 –
My wife's friend who's in her early 50s was in ICU on the weekend with covid. If she wasn't fully vaxxed she would probably be dead.
2012 HAPPENED!!!!!!!

Re: CV and mad panic behaviour

Reply #6002 –
Something I have not seen in many, many months - long queues at the Covid testing stations at Brighton East and Bentleigh East.
These areas are included in the highest rates of vaccination take-up, so what am I missing?

Re: CV and mad panic behaviour

Reply #6003 –
Quote from: Macca37 – on
These areas are included in the highest rates of vaccination take-up, so what am I missing?
The effects of social media and breakthrough infections.

Do some flights resume later this week, testing negative within 72hrs of departure is required in some cases?
"Extremists on either side will always meet in the Middle!"

Re: CV and mad panic behaviour

Reply #6004 –
Quote from: LP – on
Sputnik, Sinovax, CoronaVac, Covaxin, AZ, Pfizer, Moderna, J&J and others have already issued about 3.2 Billion doses. I doubt any of them have much to fear, because it's highly unlikely Novavax exits any large scale roll out unscathed.

I'm quite cynical because the Novavax push appears to me to be more profit orientated than science based.

For reference, because they are selling vaccines for profit Novavax, Pfizer and Moderna are about 400% more expensive on average to the end user than AZ, Sinovax, Sputnik, Covaxin, etc., etc...

From a manufacturing perspective, it might be harder to make a mRNA hybrid (Influenza / Sars-CoV-2) vaccine, than it will be to formulate the same in viral vector(AZ) or protein sub-units(Novavax). I suspect in terms of Sars-CoV-2 it would be the mRNA vaccines that might lose out longer term.

PS: About 90% of vaccinations in Indonesia to date are Sinovax / CoronaVac, Indonesia they are not a big player in mRNA or Viral Vector. I wonder if the Indonesia Novavax push part of getting in on Australia's obligation under Covax to donate millions of doses of vaccine, whatever that vaccine may be? It feels like the sort of deal Scomo might do for some nuclear sub support in return!
Novavax will be marketed as Covovax in Indonesia and will be made by the Indian Pharma Serum Institute known as SII, I believe the WHO are expecting Novavax to donate to the Covax program for smaller countries with no money via their production with SII.
Greg Hunt has said no more AZ(Covaxin) in Aus after the last batch is produced and most of that is to be given away to pacific neighbors due to the poor takeup. Penny Wong wants it to go to Indonesia and wants the Government to continue to make it for poorer countries but last time I heard Hunt speak he said this batch will be the last.
Pfizer is the dominant player in the world and will dominate the non chinese market along with Moderna and make up 75% of that market. They will also be introducing new updated vaccines by mid 2022 and are banking on the fact everyone will want their newer tweaked vaccines rather than other companies older tech.
Dont disagree Pfizer and Moderna are money makers first and health providers 2nd and according to the Financial Times will be raking in 30-$54 billion which is double what the projected earnings were initially around 30 billion according to other analysts, Moderna no slouches either with 20-$38 billion...
Pfizer have also got in first for paediatric approval as well which will form a large part of their sales next year when many countries start approving vaccine jabs for kids...
Its going to be one way traffic business wise and thats a concern in terms of producing the best vaccines vs the best marketing and production programs which is what Pfizer have over the other vaccine providers.

Re: CV and mad panic behaviour

Reply #6005 –
Quote from: ElwoodBlues1 – on
Pfizer is the dominant player in the world and will dominate the non chinese market along with Moderna and make up 75% of that market.
I've had a look at a few sources to cross check this, are you sure about that stat?

I think it may be worthwhile cross checking your source of information, I can't find anything that matches those claims, either in future orders, vaccines delivered or vaccines issued. I've checked with Nature, Nikkei and Bloomberg, they all have relative up to date stats.

Also Vaxzevria will continue to be made by CSL until the end of the 53 million dose order, production in Melbourne is expected to continue through 2022. I realise it won't continue to be called AstraZeneca, but I think that is a bit of a play on words by Hunt.
"Extremists on either side will always meet in the Middle!"
 

Re: CV and mad panic behaviour

Reply #6006 –
FiercePharma.com, The Financial Times and Airfinity were the sources for those figures from memory.
I said in my previous post that AZ would be produced by CSL to complete the contract but a lot of those doses are expected to be donated to pacific Neighbors.
Pfizer also have some viral treatment tablet coming out as well but I don't know any details.

Re: CV and mad panic behaviour

Reply #6007 –
Very interesting trend in the USA with mainstream doctors starting to take their fringe dwelling minority counterparts to task.

It looks like the bulk of the doctors working in health care are fed up with the fringe dwellers drumming them up more business than they have capacity to handle, so through official channels the mainstream medicos are taking to task the fringe doctors who have been pushing useless drugs like Ivermectin and HCQ.

In some cases the majority has even initiated group action against individuals when the peak bodies in some states failed to act due to political interference!

I wonder if mainstream journalists, lawyers and politicians will follow suit?

It looks like the majority is starting to get fed up, not sure this is a good thing though, to go to war with fanatics you must be prepared to become one!
"Extremists on either side will always meet in the Middle!"

Re: CV and mad panic behaviour

Reply #6009 –
Quote from: Mav – on
I wonder when they're going to bring out Ivermectin 2, the new, improved Ivermectin?
Pfizer's new tablet is already basically a modified protease inhibitor, so in effect a re-engineered version of drugs like Ivermectin and other similar protease inhibitors.

With some irony, some previous Ivermectin pushers and now are taking a new political position and trying to disparage the new Pfizer drug by associating or highlighting it's similarity with Ivermectin. Funny, eh, they should all be renamed Flip Wilson!
"Extremists on either side will always meet in the Middle!"

Re: CV and mad panic behaviour

Reply #6010 –
Quote from: Mav – on
Yay, a new vaccine is entering trials. This one trains a type of white blood cell, T-cells, to kill the virus as soon as it infects any cells.

A "T-cell priming" vaccine could provide better COVID-19 immunity than mRNA vaccines, Salon.
Until safety and efficacy is proven, these things are all pipe dreams.

They design / theorise all sorts of stuff In Silico, but despite being based on real world chemistry and physics much of it is closer to science fiction than science fact. After they sort out how to actually make it, not trivial and in some cases even impossible, going to In Vitro is the next step, and if it's safe then it is probably to animal trials before In Situ / Vivo trials. The whole process can take decades.

Much of the vaccines currently in use were already in development or use decades ago, that is why they became available so fast. That's were the anti-vax claims about "new" and "unproven" are bullshizen, even the newest of the set the mRNA vaccines, those techniques have been in trial and development since the early 2000s!
"Extremists on either side will always meet in the Middle!"

Re: CV and mad panic behaviour

Reply #6011 –
The article says it is about to enter a small-scale clinical trial, so it must already have succeeded in preclinical trials. The first patient will receive it in Jan 2022. The control group of 13 will receive placebos, while the other group of 13 will receive the vaccine. Interesting to read that the vaccine group will receive varying doses, which suggests they're trying to speed up the trial process by blending Phase 1 & 2. 

Re: CV and mad panic behaviour

Reply #6012 –
Quote from: Mav – on
The article says it is about to enter a small-scale clinical trial, so it must already have succeeded in preclinical trials. The first patient will receive it in Jan 2022. The control group of 13 will receive placebos, while the other group of 13 will receive the vaccine. Interesting to read that the vaccine group will receive varying doses, which suggests they're trying to speed up the trial process by blending Phase 1 & 2.
Good then, but any claims or suggestions of a technology being safer are vastly overstated.

Really, the current vaccines are not that much more risky than having a bare needle inserted, so it is very hard to see how any new technology can be significantly or substantially better and that applies to Novavax as well!
"Extremists on either side will always meet in the Middle!"

Re: CV and mad panic behaviour

Reply #6013 –
I understand why you would be concerned that promotion of new vaccines might undermine confidence in those that exist already. But the silver lining of the pandemic is that it has accelerated medical science in the way that wars have accelerated technology. The British were still flying biplanes at the start of WWII and by the end of the war they had jets. We've fast-forwarded through a decade of normal research into coronaviruses. It'll be interesting to see whether this ends up giving us better ways of suppressing the flu, for instance.

Stories like this are also a bit of an antidote to the pessimism of those who say that Covid will manage to evade vaccines, so why put your eggs in the vaccine basket. Yes, Covid may well mutate so that existing vaccines struggle to fight it (although recent articles suggest that there's reason to think Covid may find it hard to improve on Delta), but they can be tweaked or replaced by new vaccines or treatments. 

Re: CV and mad panic behaviour

Reply #6014 –
Nurses in NSW now have to prove they caught CoVid at work to receive any compensation, thats probably part of the reason that 20000 Nurses quit the job this year and gave up their registration. Why bust your Ar$e saving lives, risking your life and working double shifts for peanuts when no one gives a feck about your health, this country has some serious problems with the standard of government and the lack of common sense being shown.